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Medication and alcohol and tiredness
The two causes people forget to count as causes.
A long list of common medicines has tiredness as a side effect — beta-blockers, antihistamines, some antidepressants, some blood-pressure drugs — and it can start when the dose changes. Alcohol is a sedative that fragments the second half of the night: even two drinks measurably reduce deep sleep, and regular evening drinking leaves people tired without ever feeling drunk.
The check is a medication list review with a pharmacist or doctor, and an honest alcohol count — including the "just one or two most evenings" pattern. A two-week alcohol break is the cheapest diagnostic test there is.
Check first
Review the medicine list; try two weeks without evening alcohol.
Reference, not medical advice. If tiredness is progressive, unexplained, or comes with weight loss, fevers, night sweats or breathlessness, see a clinician. Nothing here diagnoses.